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Pharmacokinetics of the Monoclonal Antibody MHAA4549A Administered in Combination With Oseltamivir in Patients Hospitalized With Severe Influenza A Infection

MHAA4549A is a human anti‐influenza A monoclonal antibody developed to treat influenza A. We report MHAA4549A serum, nasopharyngeal, and tracheal aspirate pharmacokinetics from a phase 2b study in hospitalized patients with severe influenza A. Patients were randomized 1:1:1 into 3 groups receiving s...

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Bibliografiske detaljer
Udgivet i:J Clin Pharmacol
Main Authors: Deng, Rong, She, Gaohong, Maia, Mauricio, Lim, Jeremy J., Peck, Melicent C., McBride, Jacqueline M., Kulkarni, Priya, Horn, Priscilla, Castro, Aide, Newton, Elizabeth, Tavel, Jorge A., Hanley, William D.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7586956/
https://ncbi.nlm.nih.gov/pubmed/32621543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1652
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