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Pharmacokinetics and Diffusion into Sputum of Oseltamivir and Oseltamivir Carboxylate in Adults with Cystic Fibrosis

Oseltamivir is a prodrug of oseltamivir carboxylate (OC), a neuraminidase inhibitor used for treatment and prevention of influenza. The pharmacokinetics of these 2 compounds were investigated after a single 75-mg oseltamivir dose in 6 patients with cystic fibrosis (CF). Means ± standard deviations o...

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Bibliografski detalji
Glavni autori: Jullien, V., Hubert, D., Launay, O., Babany, G., Lortholary, O., Sermet, I.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165351/
https://ncbi.nlm.nih.gov/pubmed/21670188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00371-11
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