Pharmacokinetics and sputum penetration of ciprofloxacin in patients with cystic fibrosis.

Levels of ciprofloxacin in serum and sputum were studied for eight patients with cystic fibrosis who were infected with Pseudomonas aeruginosa. Patients were studied in a steady state on a dosage of 500 mg every 8 h. Peak levels in serum ranged from 1.27 to 5.6 mg/liter (mean, 3.16 +/- 1.27), and ab...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Smith, M J, White, L O, Bowyer, H, Willis, J, Hodson, M E, Batten, J C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1986
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176492/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3789695/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.30.4.614
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