Pharmacokinetics and sputum penetration of ciprofloxacin in patients with cystic fibrosis.

Levels of ciprofloxacin in serum and sputum were studied for eight patients with cystic fibrosis who were infected with Pseudomonas aeruginosa. Patients were studied in a steady state on a dosage of 500 mg every 8 h. Peak levels in serum ranged from 1.27 to 5.6 mg/liter (mean, 3.16 +/- 1.27), and ab...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Smith, M J, White, L O, Bowyer, H, Willis, J, Hodson, M E, Batten, J C
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1986
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176492/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3789695/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.30.4.614
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