Pharmacokinetics and sputum penetration of ciprofloxacin in patients with cystic fibrosis.

Levels of ciprofloxacin in serum and sputum were studied for eight patients with cystic fibrosis who were infected with Pseudomonas aeruginosa. Patients were studied in a steady state on a dosage of 500 mg every 8 h. Peak levels in serum ranged from 1.27 to 5.6 mg/liter (mean, 3.16 +/- 1.27), and ab...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Smith, M J, White, L O, Bowyer, H, Willis, J, Hodson, M E, Batten, J C
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1986
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176492/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3789695/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.30.4.614
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