Pharmacokinetics and sputum penetration of ciprofloxacin in patients with cystic fibrosis.

Levels of ciprofloxacin in serum and sputum were studied for eight patients with cystic fibrosis who were infected with Pseudomonas aeruginosa. Patients were studied in a steady state on a dosage of 500 mg every 8 h. Peak levels in serum ranged from 1.27 to 5.6 mg/liter (mean, 3.16 +/- 1.27), and ab...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Smith, M J, White, L O, Bowyer, H, Willis, J, Hodson, M E, Batten, J C
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1986
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176492/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3789695/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.30.4.614
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