Highly Reactive Isolevuglandins Promote Atrial Fibrillation Caused by Hypertension

Oxidative damage is implicated in atrial fibrillation (AF), but antioxidants are ineffective therapeutically. The authors tested the hypothesis that highly reactive lipid dicarbonyl metabolites, or isolevuglandins (IsoLGs), are principal drivers of AF during hypertension. In a hypertensive murine mo...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JACC Basic Transl Sci
Egile Nagusiak: Prinsen, Joseph K., Kannankeril, Prince J., Sidorova, Tatiana N., Yermalitskaya, Liudmila V., Boutaud, Olivier, Zagol-Ikapitte, Irene, Barnett, Joey V., Murphy, Matthew B., Subati, Tuerdi, Stark, Joshua M., Christopher, Isis L., Jafarian-Kerman, Scott R., Saleh, Mohamed A., Norlander, Allison E., Loperena, Roxana, Atkinson, James B., Fogo, Agnes B., Luther, James M., Amarnath, Venkataraman, Davies, Sean S., Kirabo, Annet, Madhur, Meena S., Harrison, David G., Murray, Katherine T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2020
Gaiak:
PRECLINICAL RESEARCH
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7315188/
https://ncbi.nlm.nih.gov/pubmed/32613146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2020.04.004
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