Mitochondrial Isolevuglandins Contribute to Vascular Oxidative Stress and Mitochondria-Targeted Scavenger of Isolevuglandins Reduces Mitochondrial Dysfunction and Hypertension

Hypertension remains a major health problem in Western Societies, and blood pressure is poorly controlled in a third of patients despite use of multiple drugs. Mitochondrial dysfunction contributes to hypertension and mitochondria-targeted agents can potentially improve treatment of hypertension. We...

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Publié dans:Hypertension
Auteurs principaux: Dikalova, Anna, Mayorov, Vladimir, Xiao, Liang, Panov, Alexander, Amarnath, Venkataraman, Zagol-Ikapitte, Irene, Vergeade, Aurelia, Ao, Mingfang, Yermalitsky, Valery, Nazarewicz, Rafal R., Boutaud, Olivier, Lopez, Marcos G., Billings, Frederic T., Davies, Sean, Roberts, L. Jackson, Harrison, David G., Dikalov, Sergey
Format: Artigo
Langue:Inglês
Publié: 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7666054/
https://ncbi.nlm.nih.gov/pubmed/33012204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.120.15236
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