GPx3 dysregulation impacts adipose tissue insulin receptor expression and sensitivity

Insulin receptor signaling is crucial for white adipose tissue (WAT) function. Consequently, lack of insulin receptor (IR) in WAT results in a diabetes-like phenotype. Yet, causes for IR downregulation in WAT of patients with diabetes are not well understood. By using multiple mouse models of obesit...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JCI Insight
Egile Nagusiak: Hauffe, Robert, Stein, Vanessa, Chudoba, Chantal, Flore, Tanina, Rath, Michaela, Ritter, Katrin, Schell, Mareike, Wardelmann, Kristina, Deubel, Stefanie, Kopp, Johannes Florian, Schwarz, Maria, Kappert, Kai, Blüher, Matthias, Schwerdtle, Tanja, Kipp, Anna P., Kleinridders, André
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2020
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7308064/
https://ncbi.nlm.nih.gov/pubmed/32369454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.136283
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