HSP60 reduction protects against diet-induced obesity by modulating energy metabolism in adipose tissue

OBJECTIVE: Insulin regulates mitochondrial function, thereby propagating an efficient metabolism. Conversely, diabetes and insulin resistance are linked to mitochondrial dysfunction with a decreased expression of the mitochondrial chaperone HSP60. The aim of this investigation was to determine the e...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Hauffe, Robert, Rath, Michaela, Schell, Mareike, Ritter, Katrin, Kappert, Kai, Deubel, Stefanie, Ott, Christiane, Jähnert, Markus, Jonas, Wenke, Schürmann, Annette, Kleinridders, André
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8319365/
https://ncbi.nlm.nih.gov/pubmed/34153520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2021.101276
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