How Do Branched Detergents Stabilize GPCRs in Micelles?

[Image: see text] The structural and functional properties of G protein-coupled receptors (GPCRs) are often studied in a detergent micellar environment, but many GPCRs tend to denature or aggregate in short alkyl chain detergents. In our previous work [Lee, S., et al. (2016) J. Am. Chem. Soc.138, 15...

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Detaylı Bibliyografya
Yayımlandı:Biochemistry
Asıl Yazarlar: Lee, Sangbae, Ghosh, Soumadwip, Jana, Suvamay, Robertson, Nathan, Tate, Christopher G., Vaidehi, Nagarajan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2020
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302508/
https://ncbi.nlm.nih.gov/pubmed/32437610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00183
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