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How Do Branched Detergents Stabilize GPCRs in Micelles?
[Image: see text] The structural and functional properties of G protein-coupled receptors (GPCRs) are often studied in a detergent micellar environment, but many GPCRs tend to denature or aggregate in short alkyl chain detergents. In our previous work [Lee, S., et al. (2016) J. Am. Chem. Soc.138, 15...
Enregistré dans:
| Publié dans: | Biochemistry |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American
Chemical Society
2020
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7302508/ https://ncbi.nlm.nih.gov/pubmed/32437610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00183 |
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