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Fc Gamma Receptors and Complement Component 3 Facilitate Anti-fVIII Antibody Formation

Anti-factor VIII (fVIII) alloantibodies, which can develop in patients with hemophilia A, limit the therapeutic options and increase morbidity and mortality of these patients. However, the factors that influence anti-fVIII antibody development remain incompletely understood. Recent studies suggest t...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Zerra, Patricia E., Arthur, Connie M., Chonat, Satheesh, Maier, Cheryl L., Mener, Amanda, Shin, Sooncheon, Allen, Jerry William L., Baldwin, W. Hunter, Cox, Courtney, Verkerke, Hans, Jajosky, Ryan P., Tormey, Christopher A., Meeks, Shannon L., Stowell, Sean R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7295897/
https://ncbi.nlm.nih.gov/pubmed/32582142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00905
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