Fc Gamma Receptors and Complement Component 3 Facilitate Anti-fVIII Antibody Formation

Anti-factor VIII (fVIII) alloantibodies, which can develop in patients with hemophilia A, limit the therapeutic options and increase morbidity and mortality of these patients. However, the factors that influence anti-fVIII antibody development remain incompletely understood. Recent studies suggest t...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Zerra, Patricia E., Arthur, Connie M., Chonat, Satheesh, Maier, Cheryl L., Mener, Amanda, Shin, Sooncheon, Allen, Jerry William L., Baldwin, W. Hunter, Cox, Courtney, Verkerke, Hans, Jajosky, Ryan P., Tormey, Christopher A., Meeks, Shannon L., Stowell, Sean R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7295897/
https://ncbi.nlm.nih.gov/pubmed/32582142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00905
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