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Cellular Fibronectin Containing Extra Domain A Causes Insulin Resistance via Toll-like Receptor 4
We determined the role of cellular fibronectin (CFN) containing the alternatively spliced extra domain A (FN-EDA) in causing insulin resistance (IR) through toll-like receptor 4 (TLR4). Circulating FN-EDA level was evaluated in mouse and rat IR models. Specific anti-FN-EDA antibody and TLR4 inhibito...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7272645/ https://ncbi.nlm.nih.gov/pubmed/32499562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65970-6 |
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