In Vitro and In Vivo Characterization of Potent Antileishmanial Methionine Aminopeptidase 1 Inhibitors

Leishmania major is the causative agent of cutaneous leishmaniasis (CL). No human vaccine is available for CL, and current drug regimens present several drawbacks, such as emerging resistance, severe toxicity, medium effectiveness, and/or high cost. Thus, the need for better treatment options agains...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Rodriguez, Felipe, John, Sarah F., Iniguez, Eva, Montalvo, Sebastian, Michael, Karina, White, Lyndsey, Liang, Dong, Olaleye, Omonike A., Maldonado, Rosa A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2020
Assuntos:
Experimental Therapeutics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269496/
https://ncbi.nlm.nih.gov/pubmed/32179532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01422-19
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