Methionine Aminopeptidases from Mycobacterium tuberculosis as Novel Antimycobacterial Targets

Methionine aminopeptidase (MetAP) is a metalloprotease that removes the N-terminal methionine during protein synthesis. To assess the importance of the two MetAPs in M. tuberculosis, we overexpressed and purified each of the MetAPs to near homogeneity and showed that both were active as MetAP enzyme...

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書誌詳細
主要な著者: Olaleye, Omonike, Raghunand, Tirumalai R., Bhat, Shridhar, He, Jian, Tyagi, Sandeep, Lamichhane, Gyanu, Gu, Peihua, Zhou, Jiangbing, Zhang, Ying, Grosset, Jacques, Bishai, William R., Liu, Jun O.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165048/
https://ncbi.nlm.nih.gov/pubmed/20142044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2009.12.014
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