In Vitro and In Vivo Characterization of Potent Antileishmanial Methionine Aminopeptidase 1 Inhibitors

Leishmania major is the causative agent of cutaneous leishmaniasis (CL). No human vaccine is available for CL, and current drug regimens present several drawbacks, such as emerging resistance, severe toxicity, medium effectiveness, and/or high cost. Thus, the need for better treatment options agains...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Rodriguez, Felipe, John, Sarah F., Iniguez, Eva, Montalvo, Sebastian, Michael, Karina, White, Lyndsey, Liang, Dong, Olaleye, Omonike A., Maldonado, Rosa A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2020
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269496/
https://ncbi.nlm.nih.gov/pubmed/32179532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01422-19
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