In Vitro and In Vivo Characterization of Potent Antileishmanial Methionine Aminopeptidase 1 Inhibitors

Leishmania major is the causative agent of cutaneous leishmaniasis (CL). No human vaccine is available for CL, and current drug regimens present several drawbacks, such as emerging resistance, severe toxicity, medium effectiveness, and/or high cost. Thus, the need for better treatment options agains...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Rodriguez, Felipe, John, Sarah F., Iniguez, Eva, Montalvo, Sebastian, Michael, Karina, White, Lyndsey, Liang, Dong, Olaleye, Omonike A., Maldonado, Rosa A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269496/
https://ncbi.nlm.nih.gov/pubmed/32179532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01422-19
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