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Formation of ultralong DH regions through genomic rearrangement
BACKGROUND: Cow antibodies are very unusual in having exceptionally long CDR H3 regions. The genetic basis for this length largely derives from long heavy chain diversity (DH) regions, with a single “ultralong” DH, IGHD8–2, encoding over 50 amino acids. Many bovine IGHD regions have sequence similar...
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| Publicado no: | BMC Immunol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7265228/ https://ncbi.nlm.nih.gov/pubmed/32487018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-020-00359-8 |
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