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NOSH-aspirin (NBS-1120) inhibits pancreatic cancer cell growth in a xenograft mouse model: Modulation of FoxM1, p53, NF-κB, iNOS, caspase-3 and ROS

Pancreatic cancer has poor survival rates and largely ineffective therapies. Aspirin is the prototypical anti-cancer agent but its long-term use is associated with significant side effects. NOSH-aspirin belongs to a new class of anti-inflammatory agents that were designed to be safer alternatives by...

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Publicat a:Biochem Pharmacol
Autors principals: Chattopadhyay, Mitali, Kodela, Ravinder, Santiago, Gabriela, LeCao, Thuy Tien, Nath, Niharika, Kashfi, Khosrow
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263941/
https://ncbi.nlm.nih.gov/pubmed/32061771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2020.113857
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