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Synthesis and biological activity of NOSH-naproxen (AVT-219) and NOSH-sulindac (AVT-18A) as potent anti-inflammatory agents with chemotherapeutic potential

Nitric oxide- (NO) and hydrogen sulfide- (H(2)S) releasing naproxen (NOSH-naproxen) and NO and H(2)S-releasing sulindac (NOSH-sulindac) were synthesized and their cell growth inhibitory properties were evaluated in four different human cancer cell lines. These cell lines are of adenomatous (colon, p...

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Bibliografiska uppgifter
Huvudupphovsmän: Kodela, Ravinder, Chattopadhyay, Mitali, Kashfi, Khosrow
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835719/
https://ncbi.nlm.nih.gov/pubmed/24273639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C3MD00185G
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