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NOSH-Aspirin: A Novel Nitric Oxide–Hydrogen Sulfide-Releasing Hybrid: A New Class of Anti-inflammatory Pharmaceuticals

[Image: see text] A series of new hybrids of aspirin (ASA), bearing both nitric oxide (NO) and hydrogen sulfide (H(2)S)-releasing moieties were synthesized and designated as NOSH compounds (1–4). NOSH-1 (4-(3-thioxo-3H-1,2-dithiol-5-yl) phenyl 2-((4-(nitrooxy)butanoyl)oxy) benzoate); NOSH-2 (4-(nitr...

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Detalhes bibliográficos
Main Authors: Kodela, Ravinder, Chattopadhyay, Mitali, Kashfi, Khosrow
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423220/
https://ncbi.nlm.nih.gov/pubmed/22916316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300002m
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