Synthesis and anti-cancer potential of the positional isomers of NOSH-aspirin (NBS-1120) a dual nitric oxide and hydrogen sulfide releasing hybrid

We recently reported the synthesis of NOSH-aspirin, a novel hybrid compound capable of releasing both nitric oxide (NO) and hydrogen sulfide (H(2)S). In NOSH-aspirin, the two moieties that release NO and H(2)S are covalently linked at the 1, 2 positions of acetyl salicylic acid, i.e. ortho-NOSH-aspi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Bioorg Med Chem Lett
Main Authors: Vannini, Federica, MacKessack-Leitch, Andrew C., Eschbach, Erin K., Chattopadhyay, Mitali, Kodela, Ravinder, Kashfi, Khosrow
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592841/
https://ncbi.nlm.nih.gov/pubmed/26323873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.08.023
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados