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NOSH-aspirin (NBS-1120), a novel nitric oxide- and hydrogen sulfide-releasing hybrid has enhanced chemo-preventive properties compared to aspirin, is gastrointestinal safe with all the classic therapeutic indications

Aspirin is chemopreventive; however, side effects preclude its long-term use. NOSH-aspirin (NBS-1120), a novel hybrid that releases nitric oxide and hydrogen sulfide, was designed to be a safer alternative. Here we compare the gastrointestinal safety, anti-inflammatory, analgesic, antipyretic, anti-...

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Detalhes bibliográficos
Publicado no:Biochem Pharmacol
Main Authors: Kodela, Ravinder, Chattopadhyay, Mitali, Velázquez-Martínez, Carlos A., Kashfi, Khosrow
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4656078/
https://ncbi.nlm.nih.gov/pubmed/26394025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2015.09.014
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