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Positional isomerism markedly affects the growth inhibition of colon cancer cells by NOSH-aspirin: COX inhibition and modeling()
We recently reported the synthesis of NOSH-aspirin, a novel hybrid that releases both nitric oxide (NO) and hydrogen sulfide (H(2)S). In NOSH-aspirin, the two moieties that release NO and H(2)S are covalently linked at the 1, 2 positions of acetyl salicylic acid, i.e. ortho-NOSH-aspirin (o-NOSH-aspi...
שמור ב:
| הוצא לאור ב: | Redox Biol |
|---|---|
| Main Authors: | , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Elsevier
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4556775/ https://ncbi.nlm.nih.gov/pubmed/26319435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2015.08.014 |
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