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Progress toward understanding chromosome silencing by Xist RNA
The X inactive-specific transcript (Xist) gene is the master regulator of X chromosome inactivation in mammals. Xist produces a long noncoding (lnc)RNA that accumulates over the entire length of the chromosome from which it is transcribed, recruiting factors to modify underlying chromatin and silenc...
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| Veröffentlicht in: | Genes Dev |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7263139/ https://ncbi.nlm.nih.gov/pubmed/32482714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.337196.120 |
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