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Progress toward understanding chromosome silencing by Xist RNA

The X inactive-specific transcript (Xist) gene is the master regulator of X chromosome inactivation in mammals. Xist produces a long noncoding (lnc)RNA that accumulates over the entire length of the chromosome from which it is transcribed, recruiting factors to modify underlying chromatin and silenc...

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Detalles Bibliográficos
Publicado en:Genes Dev
Autores principales: Brockdorff, Neil, Bowness, Joseph S., Wei, Guifeng
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263139/
https://ncbi.nlm.nih.gov/pubmed/32482714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.337196.120
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