Modulation of Natural HLA-B*27:05 Ligandome by Ankylosing Spondylitis-associated Endoplasmic Reticulum Aminopeptidase 2 (ERAP2)

The HLA-B*27:05 allele and the endoplasmic reticulum-resident aminopeptidases are strongly associated with AS, a chronic inflammatory spondyloarthropathy. This study examined the effect of ERAP2 in the generation of the natural HLA-B*27:05 ligandome in live cells. Complexes of HLA-B*27:05-bound pept...

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Détails bibliographiques
Publié dans:Mol Cell Proteomics
Auteurs principaux: Lorente, Elena, Fontela, Miguel G., Barnea, Eilon, Martín-Galiano, Antonio J., Mir, Carmen, Galocha, Begoña, Admon, Arie, Lauzurica, Pilar, López, Daniel
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2020
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261815/
https://ncbi.nlm.nih.gov/pubmed/32265295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA120.002014
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