Ranking the Contribution of Ankylosing Spondylitis-associated Endoplasmic Reticulum Aminopeptidase 1 (ERAP1) Polymorphisms to Shaping the HLA-B*27 Peptidome

The Endoplasmic reticulum aminopeptidase I (ERAP1) trims peptides to their optimal size for binding to Major Histocompatibility Complex class I proteins. The natural polymorphism of this enzyme is associated with ankylosing spondylitis (AS) in epistasis with the major risk factor for this disease, H...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Sanz-Bravo, Alejandro, Alvarez-Navarro, Carlos, Martín-Esteban, Adrian, Barnea, Eilon, Admon, Arie, López de Castro, José A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030728/
https://ncbi.nlm.nih.gov/pubmed/29632046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000565
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