Modulation of Natural HLA-B*27:05 Ligandome by Ankylosing Spondylitis-associated Endoplasmic Reticulum Aminopeptidase 2 (ERAP2)

The HLA-B*27:05 allele and the endoplasmic reticulum-resident aminopeptidases are strongly associated with AS, a chronic inflammatory spondyloarthropathy. This study examined the effect of ERAP2 in the generation of the natural HLA-B*27:05 ligandome in live cells. Complexes of HLA-B*27:05-bound pept...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Lorente, Elena, Fontela, Miguel G., Barnea, Eilon, Martín-Galiano, Antonio J., Mir, Carmen, Galocha, Begoña, Admon, Arie, Lauzurica, Pilar, López, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261815/
https://ncbi.nlm.nih.gov/pubmed/32265295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA120.002014
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