ST2 as checkpoint target for colorectal cancer immunotherapy

Immune checkpoint blockade immunotherapy delivers promising clinical results in colorectal cancer (CRC). However, only a fraction of cancer patients develop durable responses. The tumor microenvironment (TME) negatively impacts tumor immunity and subsequently clinical outcomes. Therefore, there is a...

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Gepubliceerd in:JCI Insight
Hoofdauteurs: Van der Jeught, Kevin, Sun, Yifan, Fang, Yuanzhang, Zhou, Zhuolong, Jiang, Hua, Yu, Tao, Yang, Jinfeng, Kamocka, Malgorzata M., So, Ka Man, Li, Yujing, Eyvani, Haniyeh, Sandusky, George E., Frieden, Michael, Braun, Harald, Beyaert, Rudi, He, Xiaoming, Zhang, Xinna, Zhang, Chi, Paczesny, Sophie, Lu, Xiongbin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7253019/
https://ncbi.nlm.nih.gov/pubmed/32376804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.136073
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