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MAL2 drives immune evasion in breast cancer by suppressing tumor antigen presentation

Immune evasion is a pivotal event in tumor progression. To eliminate human cancer cells, current immune checkpoint therapy is set to boost CD8(+) T cell–mediated cytotoxicity. However, this action is eventually dependent on the efficient recognition of tumor-specific antigens via T cell receptors. O...

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書目詳細資料
發表在:J Clin Invest
Main Authors: Fang, Yuanzhang, Wang, Lifei, Wan, Changlin, Sun, Yifan, Van der Jeught, Kevin, Zhou, Zhuolong, Dong, Tianhan, So, Ka Man, Yu, Tao, Li, Yujing, Eyvani, Haniyeh, Colter, Austyn B., Dong, Edward, Cao, Sha, Wang, Jin, Schneider, Bryan P., Sandusky, George E., Liu, Yunlong, Zhang, Chi, Lu, Xiongbin, Zhang, Xinna
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7773365/
https://ncbi.nlm.nih.gov/pubmed/32990678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI140837
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