Atractylenolide I enhances responsiveness to immune checkpoint blockade therapy by activating tumor antigen presentation

One of the primary mechanisms of tumor cell immune evasion is the loss of antigenicity, which arises due to lack of immunogenic tumor antigens as well as dysregulation of the antigen processing machinery. In a screen for small-molecule compounds from herbal medicine that potentiate T cell–mediated c...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Xu, Hanchen, Van der Jeught, Kevin, Zhou, Zhuolong, Zhang, Lu, Yu, Tao, Sun, Yifan, Li, Yujing, Wan, Changlin, So, Ka Man, Liu, Degang, Frieden, Michael, Fang, Yuanzhang, Mosley, Amber L., He, Xiaoming, Zhang, Xinna, Sandusky, George E., Liu, Yunlong, Meroueh, Samy O., Zhang, Chi, Wijeratne, Aruna B., Huang, Cheng, Ji, Guang, Lu, Xiongbin
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8121519/
https://ncbi.nlm.nih.gov/pubmed/33830945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI146832
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