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What Targets Somatic Hypermutation to the Immunoglobulin Loci?
One of the most profound enigmas in B cell biology is how activation-induced deaminase (AID) is targeted to a very small region of DNA in the immunoglobulin loci. Two specific regions are singled out: the variable region of 2 kb that contains rearranged genes on the heavy, κ light, and λ light chain...
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| Publicado no: | Viral Immunol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc., publishers
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7247024/ https://ncbi.nlm.nih.gov/pubmed/31770070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/vim.2019.0149 |
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