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AID AND SOMATIC HYPERMUTATION
In response to an assault by foreign organisms, peripheral B cells can change their antibody affinity and isotype by somatically mutating their genomic DNA. The ability of a cell to modify its DNA is exceptional in light of the potential consequences of genetic alterations to cause human disease and...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2954419/ https://ncbi.nlm.nih.gov/pubmed/20510733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0065-2776(10)05006-6 |
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