Facultative protein selenation regulates redox sensitivity, adipose tissue thermogenesis, and obesity

Oxidation of cysteine thiols by physiological reactive oxygen species (ROS) initiates thermogenesis in brown and beige adipose tissues. Cellular selenocysteines, where sulfur is replaced with selenium, exhibit enhanced reactivity with ROS. Despite their critical roles in physiology, methods for broa...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Jedrychowski, Mark P., Lu, Gina Z., Szpyt, John, Mariotti, Marco, Garrity, Ryan, Paulo, Joao A., Schweppe, Devin K., Laznik-Bogoslavski, Dina, Kazak, Lawrence, Murphy, Michael P., Gladyshev, Vadim N., Gygi, Steven P., Chouchani, Edward T., Spiegelman, Bruce M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245117/
https://ncbi.nlm.nih.gov/pubmed/32358195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2001387117
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados