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Mitochondrial reactive oxygen species and adipose tissue thermogenesis: Bridging physiology and mechanisms

Brown and beige adipose tissues can catabolize stored energy to generate heat, relying on the principal effector of thermogenesis: uncoupling protein 1 (UCP1). This unique capability could be leveraged as a therapy for metabolic disease. Numerous animal and cellular models have now demonstrated that...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Chouchani, Edward T., Kazak, Lawrence, Spiegelman, Bruce M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641863/
https://ncbi.nlm.nih.gov/pubmed/28842500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R117.789628
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