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Genetic depletion of adipocyte creatine metabolism inhibits diet-induced thermogenesis and drives obesity

Diet-induced thermogenesis is an important homeostatic mechanism that limits weight gain in response to caloric excess and contributes to the relative stability of body weight in most individuals. We previously demonstrated that creatine enhances energy expenditure through stimulation of mitochondri...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Kazak, Lawrence, Chouchani, Edward T., Lu, Gina Z., Jedrychowski, Mark P., Bare, Curtis J., Mina, Amir, Kumari, Manju, Zhang, Song, Vuckovic, Ivan, Laznik-Bogoslavski, Dina, Dzeja, Petras, Banks, Alexander S., Rosen, Evan D., Spiegelman, Bruce M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629120/
https://ncbi.nlm.nih.gov/pubmed/28844881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.08.009
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