Exportació completada — 

Combination therapy in the Col1a2(G610C) mouse model of Osteogenesis Imperfecta reveals an additive effect of enhancing LRP5 signaling and inhibiting TGFβ signaling on trabecular bone but not on cortical bone

Enhancing LRP5 signaling and inhibiting TGFβ signaling have each been reported to increase bone mass and improve bone strength in wild-type mice. Monotherapy targeting LRP5 signaling, or TGFβ signaling, also improved bone properties in mouse models of Osteogenesis Imperfecta (OI). We investigated wh...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Bone
Autors principals: Kaupp, Shannon, Horan, Dan J., Lim, Kyung-Eun, Feldman, Henry A., Robling, Alexander G., Warman, Matthew L., Jacobsen, Christina M.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232829/
https://ncbi.nlm.nih.gov/pubmed/31648079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2019.115084
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars