Bone Mineral Properties in Growing Col1a2(+/G610C) Mice, an animal model of Osteogenesis Imperfecta

The Col1a2(+/G610C) knock-in mouse, models osteogenesis imperfecta in a large old order Amish family (OOA) with type IV OI, caused by a G-to-T transversion at nucleotide 2098, which alters the gly-610 codon in the triple-helical domain of the α2(I) chain of type I collagen. Mineral and matrix proper...

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Publicado no:Bone
Main Authors: Masci, Marco, Wang, Min, Imbert, Laurianne, Barnes, Aileen M, Spevak, Lyudmila, Lukashova, Lyudmila, Yihe, Huang, Yan, Ma, Marini, Joan C, Jacobsen, Christina M, Warman, Matthew L, Boskey, Adele L
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862917/
https://ncbi.nlm.nih.gov/pubmed/27083399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2016.04.011
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