PAICS, a De Novo Purine Biosynthetic Enzyme, Is Overexpressed in Pancreatic Cancer and Is Involved in Its Progression

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with an extremely poor prognosis. There is an urgent need to identify new therapeutic targets and also understand the mechanism of PDAC progression that leads to aggressiveness of the disease. To find therapeutic targets, we analyzed da...

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Bibliographic Details
Published in:Transl Oncol
Main Authors: Agarwal, Sumit, Chakravarthi, Balabhadrapatruni V.S.K., Kim, Hyung-Gyoon, Gupta, Nirzari, Hale, Kevin, Balasubramanya, Sai Akshaya Hodigere, Oliver, Patsy G., Thomas, Dafydd G., Eltoum, Isam-Eldin A., Buchsbaum, Donald J., Manne, Upender, Varambally, Sooryanarayana
Format: Artigo
Language:Inglês
Published: Neoplasia Press 2020
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Original article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229293/
https://ncbi.nlm.nih.gov/pubmed/32422575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.100776
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