PAICS, a De Novo Purine Biosynthetic Enzyme, Is Overexpressed in Pancreatic Cancer and Is Involved in Its Progression

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with an extremely poor prognosis. There is an urgent need to identify new therapeutic targets and also understand the mechanism of PDAC progression that leads to aggressiveness of the disease. To find therapeutic targets, we analyzed da...

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Bibliografiske detaljer
Udgivet i:Transl Oncol
Main Authors: Agarwal, Sumit, Chakravarthi, Balabhadrapatruni V.S.K., Kim, Hyung-Gyoon, Gupta, Nirzari, Hale, Kevin, Balasubramanya, Sai Akshaya Hodigere, Oliver, Patsy G., Thomas, Dafydd G., Eltoum, Isam-Eldin A., Buchsbaum, Donald J., Manne, Upender, Varambally, Sooryanarayana
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press 2020
Fag:
Original article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229293/
https://ncbi.nlm.nih.gov/pubmed/32422575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.100776
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