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Enhancement of sialylation in rIgG in glyco-engineered Chinese hamster ovary cells

Since about 70% of commercial biopharmaceutical products have been produced in Chinese hamster ovary (CHO) cells, this cell line is undeniably a workhorse for biopharmaceuticals production. Meanwhile, sialic acid terminals were reported to affect anti-inflammatory activity, antibody-dependent cellul...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cytotechnology
Hauptverfasser: Nguyen, Thi Sam, Misaki, Ryo, Ohashi, Takao, Fujiyama, Kazuhito
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Netherlands 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7225233/
https://ncbi.nlm.nih.gov/pubmed/32125558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-020-00381-z
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