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Metabolic engineering of Chinese hamster ovary cells: Towards a bioengineered heparin

Heparin is the most widely used pharmaceutical to control blood coagulation in modern medicine. A health crisis that took place in 2008 led to a demand for production of heparin from non-animal sources. Chinese hamster ovary (CHO) cells, commonly used mammalian host cells for production of foreign p...

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Detalhes bibliográficos
Main Authors: Baik, Jong Youn, Gasimli, Leyla, Yang, Bo, Datta, Payel, Zhang, Fuming, Glass, Charles A., Esko, Jeffrey D., Linhardt, Robert J., Sharfstein, Susan T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299301/
https://ncbi.nlm.nih.gov/pubmed/22326251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymben.2012.01.008
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