In Vivo Crystallization of Human IgG in the Endoplasmic Reticulum of Engineered Chinese Hamster Ovary (CHO) Cells

Protein synthesis and secretion are essential to cellular life. Although secretory activities may vary in different cell types, what determines the maximum secretory capacity is inherently difficult to study. Increasing protein synthesis until reaching the limit of secretory capacity is one strategy...

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Detalhes bibliográficos
Main Authors: Hasegawa, Haruki, Wendling, John, He, Feng, Trilisky, Egor, Stevenson, Riki, Franey, Heather, Kinderman, Francis, Li, Gary, Piedmonte, Deirdre Murphy, Osslund, Timothy, Shen, Min, Ketchem, Randal R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103367/
https://ncbi.nlm.nih.gov/pubmed/21464137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.204362
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