In Vivo Crystallization of Human IgG in the Endoplasmic Reticulum of Engineered Chinese Hamster Ovary (CHO) Cells

Protein synthesis and secretion are essential to cellular life. Although secretory activities may vary in different cell types, what determines the maximum secretory capacity is inherently difficult to study. Increasing protein synthesis until reaching the limit of secretory capacity is one strategy...

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Détails bibliographiques
Auteurs principaux: Hasegawa, Haruki, Wendling, John, He, Feng, Trilisky, Egor, Stevenson, Riki, Franey, Heather, Kinderman, Francis, Li, Gary, Piedmonte, Deirdre Murphy, Osslund, Timothy, Shen, Min, Ketchem, Randal R.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
Sujets:
Cell Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103367/
https://ncbi.nlm.nih.gov/pubmed/21464137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.204362
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