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Analysis of the immunoglobulin G (IgG) secretion efficiency in recombinant Chinese hamster ovary (CHO) cells by using Citrine-fusion IgG

Biopharmaceuticals represented by immunoglobulin G (IgG) are produced by the cultivation of recombinant animal cells, especially Chinese hamster ovary (CHO) cells. It is thought that the intracellular secretion process of IgG is a bottleneck in the production of biopharmaceuticals. Many studies on t...

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Publicado en:Cytotechnology
Autores principales: Kaneyoshi, Kohei, Yamano-Adachi, Noriko, Koga, Yuichi, Uchiyama, Keiji, Omasa, Takeshi
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Netherlands 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368511/
https://ncbi.nlm.nih.gov/pubmed/30610509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-018-0276-7
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