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The production of human glucocerebrosidase in glyco‐engineered Nicotiana benthamiana plants

For the production of therapeutic proteins in plants, the presence of β1,2‐xylose and core α1,3‐fucose on plants’ N‐glycan structures has been debated for their antigenic activity. In this study, RNA interference (RNAi) technology was used to down‐regulate the endogenous N‐acetylglucosaminyltransfer...

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Detalhes bibliográficos
Publicado no:Plant Biotechnol J
Main Authors: Limkul, Juthamard, Iizuka, Sayoko, Sato, Yohei, Misaki, Ryo, Ohashi, Takao, Ohashi, Toya, Fujiyama, Kazuhito
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067671/
https://ncbi.nlm.nih.gov/pubmed/26868756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pbi.12529
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