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Engineering of human-type O-glycosylation in Nicotiana benthamiana plants

Therapeutic properties of recombinant proteins are very often affected by the composition and heterogeneity of their glycans. Conventional expression systems for recombinant pharmaceutical proteins typically do not address this problem and produce a mixture of glycoforms that are neither identical t...

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Detalhes bibliográficos
Autor principal: Strasser, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728188/
https://ncbi.nlm.nih.gov/pubmed/23147167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bioe.22857
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