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The Production of Human β-Glucocerebrosidase in Nicotiana benthamiana Root Culture

Gaucher disease is caused by a deficiency of the enzyme glucocerebrosidase (GCase). Currently, enzyme-replacement therapy using recombinant GCase produced in mammalian cells is considered the most effective treatment. Plants are an attractive alternative host for recombinant protein production due t...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Naphatsamon, Uthailak, Ohashi, Takao, Misaki, Ryo, Fujiyama, Kazuhito
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6073899/
https://ncbi.nlm.nih.gov/pubmed/29986415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19071972
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