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Targeting Trypanothione Reductase, a Key Enzyme in the Redox Trypanosomatid Metabolism, to Develop New Drugs against Leishmaniasis and Trypanosomiases

The protozoans Leishmania and Trypanosoma, belonging to the same Trypanosomatidae family, are the causative agents of Leishmaniasis, Chagas disease, and human African trypanosomiasis. Overall, these infections affect millions of people worldwide, posing a serious health issue as well as socio-econom...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Battista, Theo, Colotti, Gianni, Ilari, Andrea, Fiorillo, Annarita
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7221613/
https://ncbi.nlm.nih.gov/pubmed/32326257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25081924
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