Inhibition of Leishmania infantum trypanothione reductase by diaryl sulfide derivatives

The study presented here aimed at identifying a new class of compounds acting against Leishmania parasites, the causative agent of Leishmaniasis. For this purpose, the thioether derivatives of our in-house library have been evaluated in whole-cell screening assays in order to determine their in vitr...

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Vydáno v:J Enzyme Inhib Med Chem
Hlavní autoři: Saccoliti, Francesco, Angiulli, Gabriella, Pupo, Giovanni, Pescatori, Luca, Madia, Valentina Noemi, Messore, Antonella, Colotti, Gianni, Fiorillo, Annarita, Scipione, Luigi, Gramiccia, Marina, Di Muccio, Trentina, Di Santo, Roberto, Costi, Roberta, Ilari, Andrea
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2017
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010130/
https://ncbi.nlm.nih.gov/pubmed/28098499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2016.1250755
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